Sorting Dynamic Virtual Host Directories

[GB_001]

Hello, I'm trying to set up a dynamic virtual host for the first time.
Is it possible for be to implement some sort of folder sorting system?

For example the first ten sites are in:
/Vhosts/1/
The next ten in :
/Vhosts/2/

And so on, in order to reduce indexing load and having 400 folders in one directory.

[gvre]

A better solution (in my opinion) could be:

/vhosts/a/abcd.com
/vhosts/a/anotherdomain.com
/vhosts/b/bcde.com
/vhosts/b/bestdomain.com
/vhosts/c/cdef.com

etc.