i have this problem. I use a class called dataserver for my data access.
i create an instance of the class when app starts and call its methods from all my webforms. The code runs well on my devt machine but fails after deployment.

The class goes below

'Option Strict On
Option Explicit Off
Imports System
Imports System.Data
Imports System.Data.OleDb
Imports Microsoft.VisualBasic

Public Class DataServer
Inherits System.Web.UI.Page
Public Const MAX_PARAM_SIZE = 50
Public gcn As OleDbConnection
Private Const ParamName As String = "@P"
Private mbSuccess As Boolean
Private mds As DataSet
Private mParams() As Object

Public Sub New()
MyBase.New()
ConnectToDatabase()
End Sub

Private Sub ConnectToDatabase()
Dim strConn As String = System.Configuration.ConfigurationSettings.AppSettings("OleDB_ConnectionString")
gcn = New OleDbConnection(strConn)
gcn.Open()
End Sub

Public Function GetData(ByVal ProcName As String, _
ByVal CmdType As CommandType, _
ByVal ParamArray Params() As Object) As DataSet
Dim cmdData As New OleDbCommand
Dim lngU_limit As Integer
Dim lngL_limit As Integer
Dim blnParameterizedQuery As Boolean
Dim dsData As New DataSet
Dim daData As New OleDbDataAdapter

On Error GoTo errh
lngL_limit = LBound(Params, 1)
lngU_limit = UBound(Params, 1)

'If Not lngU_limit <= MAX_PARAM_SIZE Then Exit Function
blnParameterizedQuery = CBool(lngU_limit < MAX_PARAM_SIZE)

With cmdData
.CommandText = ProcName
.CommandType = CmdType
.Connection = gcn

If Not blnParameterizedQuery Then GoTo ExecuteCommand

'Loop thru array contents to append Parameters values
'Note: this method assumes that the client will send the required
'parameters or else a null object reference is returned
Dim pr As OleDbParameter
Dim i As Integer
For i = lngL_limit To lngU_limit
pr = New OleDbParameter
pr.ParameterName = ParamName & i
pr.Value = Params(i)
'pr.OleDbType = OleDbType.VarChar
.Parameters.Add(pr)
pr = Nothing
Next

ExecuteCommand:
daData.SelectCommand = cmdData
daData.Fill(dsData)
GetData = dsData
End With
cmdData = Nothing
Exit Function

errh:
Response.Write(Err.Description)
End Function

Public Function ExecuteProc(ByVal ProcName As String, _
ByVal ParamArray Params() As Object) As Boolean
Dim cmdData As New OleDbCommand
Dim lngU_limit As Integer
Dim lngL_limit As Integer
Dim blnParameterizedQuery As Boolean

On Error GoTo errh
lngL_limit = LBound(Params, 1)
lngU_limit = UBound(Params, 1)

If Not lngU_limit <= 100 Then Exit Function
blnParameterizedQuery = CBool(lngU_limit < 100)

With cmdData
.CommandText = ProcName
.CommandType = CommandType.StoredProcedure
.Connection = gcn

If Not blnParameterizedQuery Then GoTo ExecuteCommand

'Loop thru array contents to append Parameters values
Dim pr As OleDbParameter
Dim i As Integer
For i = lngL_limit To lngU_limit
pr = New OleDbParameter
pr.ParameterName = ParamName & i
pr.Value = Params(i)
.Parameters.Add(pr)
pr = Nothing
Next
ExecuteCommand:
.ExecuteNonQuery()
End With
cmdData = Nothing
Return True
errh:
Return False
End Function
End Class

I then create an instance of this class in Applicatio_onstart

Sub Application_Start(ByVal sender As Object, ByVal e As EventArgs)
'code to read settings from configuration file
On Error Resume Next
Dim sTitle As String = System.Configuration.ConfigurationSettings.AppSettings("AppTitle")
Application("Title") = sTitle

Dim sServer As String = System.Configuration.ConfigurationSettings.AppSettings("ServerName")
Application("ServerName") = sServer

Dim sDBName As String = System.Configuration.ConfigurationSettings.AppSettings("DatabaseName")
Application("DatabaseName") = sDBName

Application("gDataServer") = New DataServer 'new global instance to last the lifetime of app

Dim oSQLDBMO As New SQLDBMO
Dim dt As DataTable
dt = oSQLDBMO.GetProcParameters
Application("Params") = dt

End Sub

i then call the method of the class using latebinding from my webforms


Imports System.Web.UI.WebControls
Imports System.Data
'Imports System.Data.OleDb
Imports System.Web.SessionState
Imports System.IO
Imports Microsoft.VisualBasic


Public Class Agents
Inherits System.Web.UI.Page
Private mbSuccess As Boolean

#Region " Web Form Designer Generated Code "

'This call is required by the Web Form Designer.
<System.Diagnostics.DebuggerStepThrough()> Private Sub InitializeComponent()

End Sub
Protected WithEvents grdAgents As System.Web.UI.WebControls.DataGrid

#End Region

Private dsAgent As DataSet
Private bSuccess As Boolean
Private sPriv As String

Private Sub Page_Load(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles MyBase.Load
If Not IsPostBack Then
LoadData()
BindGrid(grdAgents)
End If
End Sub

Private Sub LoadData()
Dim mparams(50)
dsAgent = Application("gDataserver").Getdata("Select * from Agents", CommandType.Text, mparams)
grdAgents.DataSource = dsAgent
grdAgents.DataBind()

End Sub

End Class

When i run the app after deployment it returns the following error about latebinding

An unhandled exception was generated during the execution of the current web request. Information regarding the origin and location of the exception can be identified using the exception stack trace below.

Stack Trace:


[HttpException (0x80004005): Response is not available in this context.]
Microsoft.VisualBasic.CompilerServices.LateBinding.LateGet(Object o, Type objType, String name, Object[] args, String[] paramnames, Boolean[] CopyBack) +899
Metric.Agents.LoadData() in C:\Inetpub\wwwroot\Metric\Agents.aspx.vb:93
Metric.Agents.Page_Load(Object sender, EventArgs e) in C:\Inetpub\wwwroot\Metric\Agents.aspx.vb:77
System.EventHandler.Invoke(Object sender, EventArgs e) +0
System.Web.UI.Control.OnLoad(EventArgs e) +67
System.Web.UI.Control.LoadRecursive() +35
System.Web.UI.Page.ProcessRequestMain() +731