i meant to be dismissive.
it's going to be an uphill climb for any general-purpose framework to take off at this point, there's simply too many 500lbs gorillas to compete with.
If you could simplify the usage and minimize the weight it would help. The best thing to do, imho, would be to specialize the functionality into something unique; a niche not covered well by jQuery et al. consider JSON2, litebox, and DNDs script; they all perform usefull functionality with little fuss, and they are all relatively popular for pendant productions.
mobile ui, A/V handlers, and distributed data models are areas ripe for developing; if you can emphasize the advantages in those areas, which your framework excels at, you'll have an easier time making a pitch to programmers, most of whom seem to hate change...
still, it's a good exercise for a developer to make robust code, i encourage everyone to develop his/her own common base script to develop on top of.